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Adverse effects and contra-indications of steroids: Mnemonic (GLUCOCORTICODS) G – Glaucoma (on topical use) L – Limb muscle atrophy U – Ulcer (peptic ulcer) C – Cushing syndrome O – Osteoporosis C – Cataract (on systemic use) O – Osteonecrosis (avascular necrosis) R – C/I in Renal failure T – C/I in Tuberculosis (particu-larly ileo-caecal) I – Impair healing C – C/I in CHF O – OedemaI – Infections (due to immuno suppressant action) D – Diabetes mellitus S – Suppression of HPA-axis https://ift.tt/2LOPiZe Pharmacy Study Material https://ift.tt/2C9KnlW

Pharmacy Study Material https://ift.tt/2C9KnlW
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Diazotization Titrations

Free pharmacy material Diazotization Titrations INTRODUCTION The diazotization titration is nothing but the conversion of the primary aromatic amine to a diazonium compound. This process was first discovered in 1853 and was applied to the synthetic dye industry. The reaction mechanism was first proposed by Peter Griessin. In this method, the primary aromatic amine is reacted with the sodium nitrite in acidic medium to form a diazonium salt. This method is first used in the determination of dyes. PRINCIPLE The principle involved in this method is that the primary aromatic amine present in the sample reacts with the sodium nitrite in the presence of acid such as hydrochloric acid to obtain a diazonium salt. R − NH 2 + NaNO 2 +HCl R − N + ≡ N − Cl − + NaCl + H 2 O Sodium nitrite is added to the solution of amine in the presence of acid at 0–5 °C. The amine reacts with the nitrous acid to form nitrosamine, which is followed by the tautomerisation and the water mol...
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Nephelometry and Turbidimetry

Free pharmacy material Nephelometry and Turbidimetry INTRODUCTION This is mainly used to determine the scattering of the light by the suspended particles present in the sample solution. The instruments used for the measurement of the scattering are called nephelometer and turbidimeters. The choice between the nephelometry and turbidimetry depends upon the fraction of light scattered. This light scattering by the particles which are present in the colloids is known as the Tyndall affect. Nephelometry is the measurement of the scattered light by the suspended particles at right angles to the incident beam. This method is mainly used for the determination of the low concentration suspensions. Turbidimetry is the measurement of the transmitted light by the suspended particles to the incident beam. This is used for the determination of the high concentration suspensions. PRINCIPLE Light scattering is the physical character of the sample which will depend on the following: ...
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Electrogravimetry

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