Free pharmacy material Sulphonamides, Sulphones, and Dihydrofolate Reductase Inhibitors The sulphonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. The sulphonamides and sulphone antibacterials as well as the 2,4-diaminopyrimidine antifolates continue to be successful chemotherapeutic agents. 24.1 SULPHONAMIDES The sulphonamide drugs were the first effective chemotherapeutic agents to be employed systemically for the prevention of bacterial infections in human beings. These are totally synthetic substances that are produced by relatively simple chemical synthesis. Sulphonamide drugs are a group of synthetic antimicrobial drugs that have a broad spectrum of use with respect to grampositive as well as gram-negative micro-organisms. They were introduced into medical practice even before the discovery of penicillins. Sulphonamide drugs are derivatives of sulphanilamide. The advent of penicillin and s...
Amoxicillin As a cornerstone of modern medicine, this antibiotic has saved countless lives since its introduction in the 1970s. But with great power comes great responsibility! Here is everything you need to know about this "super-penicillin." 💊 Pharmacist Focus: Understanding Amoxicillin Amoxicillin is a semi-synthetic antibiotic that belongs to the Penicillin family. It is "bactericidal," meaning it doesn't just stop bacteria from growing—it actively destroys them. 🔍 Fast Facts: The Family Tree: It was developed in 1972 as an improvement over Penicillin G. It is better absorbed by the body, meaning it can fight infections more effectively from the inside out. How it Works: It attacks the "armor" (cell walls) of bacteria. Without this wall, the bacteria cannot survive the pressure of their own internal fluids and they eventually burst! Not for Viruses: Amoxicillin only works on bacteria . It will not help you recover from a col...