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Local Anaesthetics Chemistry

Free pharmacy material Local Anaesthetics INTRODUCTION Local anaesthetics are medications used for the purpose of temporary and reversible elimination of painful feelings in specific areas of the body by blocking transmission of nerve fibre impulses. These drugs, unlike general anaesthetics, cause a loss of feeling in specific areas while keeping the patient conscious. Local anaesthetics are used for pain relief, soreness, itching, and irritation associated with disturbance of the integrity of the skin and mucous membranes (cuts, bites, wounds, rashes, allergic conditions, fungal infections, skin sores, and cracking). They are used during opthalmological procedures such as tonometry and gonioscopy, removal of foreign bodies, and minor surgical interventions. Local anaesthetics are widely used in surgery, gynaecology, and dentistry. In certain cases, local anaesthetics (lidocaine, procainamide) can be used as anti-arrhythmic drugs. IDEAL PROPERTIES OF LOCAL ANAESTHETICS ...